Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p032 | (1) | WCRB2014

The detailed localization of meiotic cohesin subunits, RAD21L and REC8, in mouse spermatocytes

Rong Mei , Matsuda Atsushi , Hiraoka Yasushi , Lee Jibak

Introduction: In meiosis, homologous chromosomes pair, synapse, and recombine with their partners in parallel with the formation of the synaptonemal complex, a tripartite structure with two axial elements connected by transverse filaments. It has been demonstrated that two meiosis-specific cohesin subunits, RAD21L and REC8 are essential for the formation of the axial elements and homologous chromosome recombination. However, it is unknown how they are involved in synapsis and ...